What is Perlane®?

Like Restylane®, Perlane® is a clear gel formulation of a natural hyaluronic acid specifically formulated to add fullness like your body’s own hyaluronic acid.

Just like Restylane®, Perlane® adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).

What makes Perlane® different is the average size of the particles and the depth of injection. On average, the gel particles in Perlane® are larger than those in Restylane®, which makes Perlane® a good choice for wrinkles that benefit from a deeper injection into the skin.

What is Perlane® made of?

Perlane® is composed of hyaluronic acid, a natural component of our skin.

How does Perlane® differ from Restylane®?

Perlane® is a denser cosmetic dermal filler than Restylane® because the individual particle sizes of the hyaluronic acid molecule in Perlane® are substantially larger. Because of its greater density, Perlane® is primarily used for deeper facial folds and facial contouring.

Why is hyaluronic acid so important?

Healthy, young skin is smooth and elastic and contains a large amount of hyaluronic acid. The lower skin layer, also called the dermis, primarily contains two protein fibers: collagen and elastin. Together collagen and elastin create a framework for supporting essential skin structures. The dermis is hydrated by floating these proteins and other vital skin structures in a “sea” of hyaluronic acid. Hyaluronic acid is capable of binding 1000 times its own weight in water and is essential for maintaining skin integrity and fullness.

The ability of our skin to produce hyaluronic acid slowly diminishes with time. As a consequence of this volume loss, our skin becomes looser leading to wrinkles and an aged appearance. Treatment with Perlane® replaces lost hyaluronic acid in the skin, restoring a healthier, more youthful appearance.

How does Perlane® differ from other hyaluronic acid-based products?

Perlane® is free from animal proteins eliminating the risk for transmission of animal-based disease or allergy to animal proteins.

What areas can be treated with Perlane®?

Perlane® is primarily used to correct facial lines, wrinkles and folds:

  • Nasolabial Folds (Deep smile lines)
  • Lines at the corner of the mouth (Marionette Lines)
  • Lifting and providing volume to the mid face (facial contouring)
  • Cheek depressions and facial scars
  • Jowl Area

Visit the Restylane® and Perlane® official website

View our Perlane® anti-aging treatment presentation.

An Experienced Hand Makes the Difference…

Precise placement technique means you get the best and longest lasting results from your Perlane®

Will my facial expressions continue to look natural?

Our philosophy is to produce a natural result. Although the results are visible, a treatment with Restylane® dermal filler will not radically change your facial appearance or make you look as if you “had work done The trick is to make sure you retain a natural ability to show emotions through facial movements.

We’ve all seen the “frozen face” on someone who’s been overdone. With our extensive experience and expert touch, you’ll never have to worry about looking unnatural.

Is treatment with Perlane® safe?

Perlane has a highly favorable safety profile and has been used extensively worldwide by dermatologists and plastic surgeons since 1996. The most commonly reported side effects include temporary redness and swelling at the injection site which typically resolves within seven days.

Is treatment with Perlane® painful?

Perlane is injected in tiny aliquots using an ultrafine needle. Topically applied local numbing creams are often used to minimize any discomfort during this quick procedure. The treatment is performed literally in a matter of minutes. No specific care is needed after the treatment.

Can I use Perlane with Botox?

Yes, in many areas we utilize both products which are not only complementary but in many cases the effects are synergistic. By relaxing muscle movement with botox before injecting Perlane, we often obtain a better aesthetic correction and the Restylane treatments tend to last longer.

How long does Perlane® last?

Results with Perlane® are practically instantaneous and typically last up to six months. Further, in three recent clinical studies of 150 patients each, approximately 70% of patients maintained improvement for six months after just one Perlane® treatment.

Is treatment with Perlane® safe?

Perlane® has a highly favorable safety profile and has been used extensively worldwide by dermatologists and plastic surgeons since 1996. The most commonly reported side effects include temporary redness and swelling at the injection site which typically resolves within seven days.


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